Cholinergic Neuromodulation Changes Phase Response Curve Shape and Type in Cortical Pyramidal Neurons
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چکیده
منابع مشابه
Cholinergic Neuromodulation Changes Phase Response Curve Shape and Type in Cortical Pyramidal Neurons
Spike generation in cortical neurons depends on the interplay between diverse intrinsic conductances. The phase response curve (PRC) is a measure of the spike time shift caused by perturbations of the membrane potential as a function of the phase of the spike cycle of a neuron. Near the rheobase, purely positive (type I) phase-response curves are associated with an onset of repetitive firing th...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2008
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0003947